Biostatistics III
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Description
Biostatistics is the branch of statistics developed for applications within the biomedical, pharmaceutical and health sciences. These methods are fundamental to contemporary medical research. They play a key role in evaluating treatments for diseases such as cancer and heart disease, in predicting the spread and incidence of epidemics and in evaluating the risk associated with factors such as obesity or exposure to electromagnetic radiation. This course provides an introduction to the design and analysis of clinical trials and epidemiological studies, and methods for the analysis of biostatistical data.
Objective
Content
Topics covered are: the role of randomisation and ethical considerations, Phase I to Phase IV trials, the Data and Safety Monitoring Board; methods of randomisation, unrestricted and restricted randomisation, random permuted blocks, biased coin designs, stratification, minimisation; trial size, fixed, sequential and group sequential trials, factorial trials, crossover trials and equivalence trials; epidemiology, cohort, case-control and related epidemiological studies, models for disease association, relative risk, odds ratio, attributable risk; diagnostic tests and screening, meta-analysis, survival analysis.
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| Year |
Semester |
Level |
Units |
| 2012 |
2 |
3 |
3 |
Delivery
36 hours lectures, tutorials and practicals
Assessment
Ongoing assessment 30%, exam 70%.
Graduate attributes
Linkage past
Prerequisite is MATHS 1007A/B Mathematics I or
MATHS 1000A/B Mathematics IM, and STATS 1000 Statistical Practice I
or equivalent course.
It is also assumed that students have completed at least 4 units
of the second year Statistics courses or equivalent. It is
intended that Biostatistics III should be accessible to a
broad range of students with some mathematical and statistical
background.
Linkage present
No present linkages have been noted.
Linkage future
This course is not recorded as prequisite for other courses.
Restrictions
None.
Recommended text
None.
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